Beilstein J. Org. Chem.2016,12, 531–536, doi:10.3762/bjoc.12.52
cyclohexenones 13/36 in the presence of LiOt-Bu to give brominatedanthraquinones 14/38 in good yields. Darzens condensation of 30 was shown to give chain-elongated anthraquinone 32. Alkaline hydrolysis of 38 furnished 39 representing desulfoproisocrinin F.
Keywords: brominatedanthraquinones; Darzens
biomimetic aldol condensations [17][18][19][20][21][22][23], and reports on the synthesis of brominatedanthraquinones are scare [12][13][14][15]. Having inspired by the convergence and the regiochemical integrity of the Hauser annulation [24][25][26][27][28][29][30], we explored it for the construction of